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CL 316243
CAS No. 183720-02-7
CL 316243 ( BTA 243 )
Catalog No. M12836 CAS No. 183720-02-7
CL 316243 (BTA 243) is a potent, highly selective, orally active β3-adrenoceptor agonist with EC50 of 3 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameCL 316243
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NoteResearch use only, not for human use.
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Brief DescriptionCL 316243 (BTA 243) is a potent, highly selective, orally active β3-adrenoceptor agonist with EC50 of 3 nM.
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DescriptionCL 316243 (BTA 243) is a potent, highly selective, orally active β3-adrenoceptor agonist with EC50 of 3 nM; Displays >10000-fold selective over β1 and β2 receptors; Significantly increases brown adipose tissue thermogenesis and resting metabolic rate in mice, also increases the concentration of insulin receptors and decreases the levels of serum insulin and blood glucose during the glucose overloading test.Obesity Discontinued
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SynonymsBTA 243
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PathwayAngiogenesis
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TargetAdrenergic Receptor
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RecptorAdrenergic Receptor
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Research AreaMetabolic Disease
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IndicationObesity
Chemical Information
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CAS Number183720-02-7
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Formula Weight421.83
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Molecular FormulaC20H20ClNO7
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(CC1=CC2=C(C=C1)OC(O2)(C(=O)O)C(=O)O)NCC(C3=CC(=CC=C3)Cl)O
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Chemical Name5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Berlan M, et al. J Pharmacol Exp Ther. 1994 Mar;268(3):1444-51.
2. Himms-Hagen J, et al. Am J Physiol. 1994 Apr;266(4 Pt 2):R1371-82.
3. Yoshida T, et al. Life Sci. 1994;54(7):491-8.
2. Himms-Hagen J, et al. Am J Physiol. 1994 Apr;266(4 Pt 2):R1371-82.
3. Yoshida T, et al. Life Sci. 1994;54(7):491-8.
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